Angiogenic Potential of 3-Nitro-4-Hydroxy Benzene Arsonic Acid (Roxarsone)
نویسندگان
چکیده
منابع مشابه
Angiogenic Potential of 3-Nitro-4-Hydroxy Benzene Arsonic Acid (Roxarsone)
BACKGROUND Roxarsone (3-nitro-4-hydroxy benzene arsonic acid) is an arsenic compound widely used in the poultry industry as a feed additive to prevent coccidiosis, stimulate growth, and to improve tissue pigmentation. Little is known about the potential human health effects from roxarsone released into the environment from chicken waste or from residual compound in chicken products. OBJECTIVE...
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The extensive use of 3-nitro-4-hydroxybenzene arsonic acid (roxarsone) in the production of broiler chickens can lead to increased soil arsenic concentration and arsenic contaminated dust. While roxarsone is the dominant arsenic species in fresh litter, inorganic As (V) predominates in composted litter. Microbial activity has been implicated as the cause, but neither the specific processes nor ...
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The asymmetric unit of the title compound, C(8)H(6)N(2)O(4), consists of two independent mol-ecules with similar geometries, each adopting a trans configuration about the olefinic double bond. The two mol-ecules are both almost planar (r.m.s. deviations = 0.034 and 0.035 Å) and form a dihedral angle of 83.62 (2)°. Short N⋯O contacts [2.834 (3)-2.861 (3) Å] are observed between the nitro groups ...
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We describe a simple liquid-chromatographic assay of urinary 4-hydroxy-3-methoxymandelic (vanillylmandelic) acid, 4-hydroxy-3-methoxyphenylacetic (homovanillic) acid, and 5-hydroxy-3-indoleacetic acid with electrochemical detection, with direct injection of the sample. The first two analytes are measured simultaneously; 5-hydroxy-3-indoleacetic acid is measured separately. Chromatographic condi...
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In the title compound, C12H10N4O2, the dihedral angle between the aromatic rings is 43.18 (16)°. The nitro group is rotated from its attached ring by 7.8 (2)° and a short intra-molecular N-H⋯N contact occurs. In the crystal, the mol-ecules are linked by N-H⋯N and C-H⋯O hydrogen bonds, generating a three-dimensional network.
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2008
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.10885